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Article

Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

PloS one - 1 Jan 2013

Zhang Zhehao, Wang Jen-Chyong, Howells William, Lin Peng, Agrawal Arpana, Edenberg Howard J, Tischfield Jay A, Schuckit Marc A, Bierut Laura J, Goate Alison, Rice John P

Abstract excerpt

Both linkage and association studies have been successfully applied to identify disease susceptibility genes with genetic markers such as microsatellites and Single Nucleotide Polymorphisms (SNPs). As one of the traditional family-based studies, the Transmission/Disequilibrium Test (TDT) measures the over-transmission of an allele in a trio from its heterozygous parents to the affected offspring and can be...

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Identifiers

PMID: 23691058
DOI: 10.1371/journal.pone.0063526
PMCID: PMC3653954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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