The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.

doi:10.1017/s001667230100533x

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The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.

Genetical research - 1 Dec 2001

Deng H W, Chen W M

Abstract excerpt

The transmission disequilibrium test (TDT) customarily uses affected children and their parents (often case-parent trios, TDTD). Control-parent trios are necessary to guard against spurious significant results due to segregation distortion but are not generally utilized in the identification of disease susceptibility loci (DSL). Controls are often easy to recruit and the TDT can easily be extended to include...

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The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.

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The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.

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