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Article

Fatty acid desaturase 1 gene polymorphisms control human hepatic lipid composition.

Hepatology (Baltimore, Md.) - 1 Jan 2015

Wang Libo, Athinarayanan Shaminie, Jiang Guanglong, Chalasani Naga, Zhang Min, Liu Wanqing

Abstract excerpt

UNLABELLED: Fatty acid desaturase (FADS) genes and their variants have been associated with multiple metabolic phenotypes, including liver enzymes and hepatic fat accumulation, but the detailed mechanism remains unclear. We aimed to delineate the role of FADSs in modulating lipid composition in human liver. We performed a targeted lipidomic analysis of a variety of phospholipids, sphingolipids, and ceramides...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25123259
DOI: 10.1002/hep.27373
PMCID: PMC4280302

Genes

FADS1
FADS2
FADS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fatty acid desaturase 1 gene polymorphisms control human hepatic lipid composition.PMID 25123259Read ↗

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