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Article

FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression.

Clinical epigenetics - 29 Aug 2018

He Zhen, Zhang Rong, Jiang Feng, Zhang Hong, Zhao Aihua, Xu Bo, Jin Li, Wang Tao, Jia Wei, Jia Weiping, Hu Cheng

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWASs) have shown that genetic variants are important determinants of free fatty acid levels. The mechanisms underlying the associations between genetic variants and free fatty acid levels are incompletely understood. Here, we aimed to identify genetic markers that could influence diverse fatty acid levels in a Chinese population and uncover the molecular mechanisms in...

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Source

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Identifiers

PMID: 30157936
DOI: 10.1186/s13148-018-0545-5
PMCID: PMC6114248

Genes

FADS1
FADS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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