Article
Dietary omega-3 polyunsaturated fatty acids relate to lower liver lipids and adipose-tissue insulin resistance, modulated by fatty acid desaturase 1 rs174546 in type 2 diabetes.
Clinical nutrition (Edinburgh, Scotland) - 1 Jul 2026
Suzuki Keita, Bódis Kálmán B, Pafili Kalliopi, Hara Akinori, Knebel Birgit, Schlesinger Sabrina, Schrauwen-Hinderling Vera, Trenkamp Sandra, Al-Hasani Hadi, Kahl Sabine, Herder Christian, Wagner Robert, Takamura Toshinari, Nakamura Hiroyuki, Roden Michael
Abstract excerpt
BACKGROUND & AIMS: Type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD) frequently coexist and increase cardiovascular risk. Although habitual omega-3 (ω3) polyunsaturated fatty acids (PUFAs) may improve cardiovascular risk, their metabolic effects in type 2 diabetes and MASLD remain unclear. We hypothesized that ω3-PUFA intake reduces hepatocellular lipid content (HCL) in...
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