Article
FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.
International journal of environmental research and public health - 28 May 2017
Huang Meng-Chuan, Chang Wen-Tsan, Chang Hsin-Yu, Chung Hsin-Fang, Chen Fang-Pei, Huang Ya-Fang, Hsu Chih-Cheng, Hwang Shang-Jyh
Abstract excerpt
Polyunsaturated fatty acids (PUFA) correlate with risk of dyslipidemia and cardiovascular diseases. Fatty acid desaturase (FADS) single nucleotide polymorphisms (SNPs) modulate circulating PUFA concentrations. This study examined influence of FADS1 and FADS2 genetic variants on desaturase activities and blood lipid concentrations in type 2 diabetes patients, and further assessed their interrelationships. Selected...
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