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Article

Integrative analysis of GWASs, human protein interaction, and gene expression identified gene modules associated with BMDs.

The Journal of clinical endocrinology and metabolism - 1 Nov 2014

He Hao, Zhang Lei, Li Jian, Wang Yu-Ping, Zhang Ji-Gang, Shen Jie, Guo Yan-Fang, Deng Hong-Wen

Abstract excerpt

CONTEXT: To date, few systems genetics studies in the bone field have been performed. We designed our study from a systems-level perspective by integrating genome-wide association studies (GWASs), human protein-protein interaction (PPI) network, and gene expression to identify gene modules contributing to osteoporosis risk. METHODS: First we searched for modules significantly enriched with bone mineral density...

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Share to Bone Density
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 25119315
DOI: 10.1210/jc.2014-2563
PMCID: PMC4223444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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