Article
Prediction of osteoporosis candidate genes by computational disease-gene identification strategy.
Journal of human genetics - 1 Jan 2008
Huang Qing-Yang, Li Gloria H Y, Cheung William M W, Song You-Qiang, Kung Annie W C
Abstract excerpt
Osteoporosis is a complex disease with a strong genetic component. To date, more than 20 genome-wide linkage scans across multiple populations have been launched to hunt for osteoporosis susceptibility genes. Some significant or suggestive chromosomal regions of linkage to bone mineral density have been identified and replicated in genome-wide linkage screens. However, identification of key candidate genes within...
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