Article

Identification of a core module for bone mineral density through the integration of a co-expression network and GWAS data

2019-10-13

Abstract excerpt

Recently, the “omnigenic” model of the genetic architecture of complex traits proposed two general categories of causal genes, core and peripheral. Core genes are hypothesized to play a direct role in regulating disease; thus, their identification has the potential to reveal critical regulators and novel therapeutic targets. Here, we sought to identify genes with “core-like” characteristics for bone mineral densit...

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Literature Corpus work: 30af77c7-38ad-5f18-8549-b0e6de30aedb
DOI: 10.1101/803197

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