Article
Cumulative effects of genetic markers and the detection of advanced colorectal neoplasias by population screening.
Clinical genetics - 1 Sept 2015
Kurlapska A, Serrano-Fernández P, Baszuk P, Gupta S, Starzyńska T, Małecka-Panas E, Dabrowski A, Dębniak T, Kurzawski G, Suchy J, Rogoza-Mateja W, Scott R J, Lubiński J
Abstract excerpt
Genetic markers associated with colorectal cancer may be used in population screening for the early identification of patients at elevated risk of disease. We genotyped 3059 individuals with no cancer family history for eight markers previously associated with colorectal cancer. After colonoscopy, the genetic profile of cases with advanced colorectal neoplasia (213) was compared with the rest (2846). rs2066847...
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