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Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2010

Xiong Fang, Wu Chen, Bi Xinyu, Yu Dianke, Huang Liming, Xu Jian, Zhang Tongwen, Zhai Kan, Chang Jiang, Tan Wen, Cai Jianqiang, Lin Dongxin

Abstract excerpt

BACKGROUND: Recent genome-wide association studies have identified 10 single nucleotide polymorphisms (SNP) associated with colorectal cancer (CRC) in Caucasians. This study evaluated the effects of these newly identified SNPs in a Chinese population. METHODS: We assessed the associations of these 10 SNPs with CRC in a case-control study that consisted of 2,124 cases and 2,124 controls. Odds ratios (OR) and 95%...

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PMID: 20530476
DOI: 10.1158/1055-9965.EPI-10-0210

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