Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial Colorectal Cancer and Genetic Susceptibility: Colorectal Risk Variants in First-Degree Relatives of Patients With Colorectal Cancer.

Clinical and translational gastroenterology - 3 Feb 2021

Gargallo-Puyuelo Carla J, Lanas Ángel, Carrera-Lasfuentes Patricia, Ferrández Ángel, Quintero Enrique, Carrillo Marta, Alonso-Abreu Inmaculada, García-González María Asunción

Abstract excerpt

INTRODUCTION: Epidemiological studies estimate that having a first-degree relative (FDR) with colorectal cancer (CRC) increases 2-fold to 3-fold the risk of developing the disease. Because FDRs of CRC patients are more likely to co-inherit CRC risk variants, we aimed to evaluate potential differences in genotype distribution of single nucleotide polymorphisms (SNPs) related to CRC risk between FDRs of patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Case-Control Studies

Share to Colorectal Neoplasms

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 33534415
DOI: 10.14309/ctg.0000000000000301
PMCID: PMC7861964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial Colorectal Cancer and Genetic Susceptibility: Colorectal Risk Variants in First-Degree Relatives of Patients With Colorectal Cancer.PMID 33534415Read ↗

Genetic susceptibility in the development of colorectal adenomas according to family history of colorectal cancer.Semantic proximity Read ↗

Low-penetrance susceptibility variants in familial colorectal cancer.Semantic proximity Read ↗

Genetic predisposition to colorectal cancer: syndromes, genes, classification of genetic variants and implications for precision medicineSemantic proximity Read ↗

Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer GenesSemantic proximity Read ↗

Susceptibility genetic variants associated with early-onset colorectal cancer.Semantic proximity Read ↗

Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population.Semantic proximity Read ↗

The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery.Semantic proximity Read ↗

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family historySemantic proximity Read ↗

A paradigm shift in genetic predisposition to colorectal cancer: the impact of germline multigene panel testing on diagnosis and management.Semantic proximity Read ↗

Seeking genetic susceptibility variants for colorectal cancer: the EPICOLON consortium experience.Semantic proximity Read ↗

Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer.Semantic proximity Read ↗

Genetic variations in colorectal cancer risk and clinical outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.