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Article

Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening.

Future oncology (London, England) - 1 Feb 2016

Jenkins Mark A, Makalic Enes, Dowty James G, Schmidt Daniel F, Dite Gillian S, MacInnis Robert J, Ait Ouakrim Driss, Clendenning Mark, Flander Louisa B, Stanesby Oliver K, Hopper John L, Win Aung K, Buchanan Daniel D

Abstract excerpt

AIM: To determine whether single nucleotide polymorphisms (SNPs) can be used to identify people who should be screened for colorectal cancer. METHODS: We simulated one million people with and without colorectal cancer based on published SNP allele frequencies and strengths of colorectal cancer association. We estimated 5-year risks of colorectal cancer by number of risk alleles. RESULTS: We identified 45 SNPs...

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Identifiers

PMID: 26846999
DOI: 10.2217/fon.15.303
PMCID: PMC4976832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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