Article
ABCC5 transporter is a novel type 2 diabetes susceptibility gene in European and African American populations.
Annals of human genetics - 1 Sept 2014
Direk Kenan, Lau Winston, Small Kerrin S, Maniatis Nikolas, Andrew Toby
Abstract excerpt
Numerous functional studies have implicated PARL in relation to type 2 diabetes (T2D). We hypothesised that conflicting human association studies may be due to neighbouring causal variants being in linkage disequilibrium (LD) with PARL. We conducted a comprehensive candidate gene study of the extended LD genomic region that includes PARL and transporter ABCC5 using three data sets (two European and one African...
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