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Article

Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene.

Genome research - 1 Jul 2004

Soranzo Nicole, Cavalleri Gianpiero L, Weale Michael E, Wood Nicholas W, Depondt Chantal, Marguerie Richard, Sisodiya Sanjay M, Goldstein David B

Abstract excerpt

The difficulty of fine localizing the polymorphisms responsible for genotype-phenotype correlations is emerging as an important constraint in the implementation and interpretation of genetic association studies, and calls for the definition of protocols for the follow-up of associated variants. One recent example is the 3435C>T polymorphism in the multidrug transporter gene ABCB1, associated with protein...

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Share to Anticonvulsants
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Drug Resistance, Multiple

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Source

Open in PubMed Open full text

Identifiers

PMID: 15197162
DOI: 10.1101/gr.1965304
PMCID: PMC442149

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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