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Article

A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women.

PloS one - 1 Jan 2017

Haddad Stephen A, Palmer Julie R, Lunetta Kathryn L, Ng Maggie C Y, Ruiz-Narváez Edward A

Abstract excerpt

SNP rs7903146 in the Wnt pathway's TCF7L2 gene is the variant most significantly associated with type 2 diabetes to date, with associations observed across diverse populations. We sought to determine whether variants in other Wnt pathway genes are also associated with this disease. We evaluated 69 genes involved in the Wnt pathway, including TCF7L2, for associations with type 2 diabetes in 2632 African American...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diabetes Mellitus, Type 2

Share to Polymorphism, Single Nucleotide

Share to Transcription Factor 7-Like 2 Protein

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Source

Open in PubMed Open full text

Identifiers

PMID: 28253288
DOI: 10.1371/journal.pone.0172577
PMCID: PMC5333820

Genes

ECE2
PSMD2

Provenance

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