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Article

The interaction of APOE genotype by age in amnestic mild cognitive impairment: a voxel-based morphometric study.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Chen Jiu, Shu Hao, Wang Zan, Liu Duan, Shi Yongmei, Zhang Xiangrong, Zhang Zhijun

Abstract excerpt

The apolipoprotein E (APOE) gene has been confirmed as the major genetic risk factor for the conversion of amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD). The present study was to assess whether there was a specific interaction of APOE by the aging process on brain morphology in aMCI. The analysis of gray matter (GM) voxel-based morphometry was performed in 85 aMCI and 100 healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25114090
DOI: 10.3233/JAD-141677

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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