Article
Impact of Apolipoprotein E4 Polymorphism on the Gray Matter Volume and the White Matter Integrity in Subjective Memory Impairment without White Matter Hyperintensities: Voxel-Based Morphometry and Tract-Based Spatial Statistics Study under 3-Tesla MRI.
Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Jan 2000
Lee Young-Min, Ha Ji-Kyung, Park Je-Min, Lee Byung-Dae, Moon EunSoo, Chung Young-In, Kim Ji-Hoon, Kim Hak-Jin, Mun Chi-Woong, Kim Tae-Hyung, Kim Young-Hoon
Abstract excerpt
OBJECTIVE: The aim of this study is to compare gray matter (GM) volume and white matter (WM) integrity in Apolipoprotein E4 (ApoE ε4) carriers with that of ApoE ε4 noncarriers using the voxel-based morphometry and diffusion tensor imaging (DTI) to investigate the effect of the ApoE ε4 on brain structures in subjective memory impairment (SMI) without white matter hyperintensities (WMH). METHODS: Altogether, 26...
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