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Article

Virus-like nanoparticle and DNA vaccination confers protection against respiratory syncytial virus by modulating innate and adaptive immune cells.

Nanomedicine : nanotechnology, biology, and medicine - 1 Jan 2015

Ko Eun-Ju, Kwon Young-Man, Lee Jong Seok, Hwang Hye Suk, Yoo Si-Eun, Lee Yu-Na, Lee Young-Tae, Kim Min-Chul, Cho Min Kyoung, Lee You Ri, Quan Fu-Shi, Song Jae-Min, Lee Sujin, Moore Martin L, Kang Sang-Moo

Abstract excerpt

Respiratory syncytial virus (RSV) is an important human pathogen. Expression of virus structural proteins produces self-assembled virus-like nanoparticles (VLP). We investigated immune phenotypes after RSV challenge of immunized mice with VLP containing RSV F and G glycoproteins mixed with F-DNA (FdFG VLP). In contrast to formalin-inactivated RSV (FI-RSV) causing vaccination-associated eosinophilia, FdFG VLP...

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Identifiers

PMID: 25109662
DOI: 10.1016/j.nano.2014.07.013
PMCID: PMC4280318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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