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Article

Innate and adaptive cellular phenotypes contributing to pulmonary disease in mice after respiratory syncytial virus immunization and infection.

Virology - 1 Nov 2015

Lee Young-Tae, Kim Ki-Hye, Hwang Hye Suk, Lee Youri, Kwon Young-Man, Ko Eun-Ju, Jung Yu-Jin, Lee Yu-Na, Kim Min-Chul, Kang Sang-Moo

Abstract excerpt

Respiratory syncytial virus (RSV) is the major leading cause of infantile viral bronchiolitis. However, cellular phenotypes contributing to the RSV protection and vaccine-enhanced disease remain largely unknown. Upon RSV challenge, we analyzed phenotypes and cellularity in the lung of mice that were naïve, immunized with formalin inactivated RSV (FI-RSV), or re-infected with RSV. In comparison with naïve and live...

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Identifiers

PMID: 26196232
DOI: 10.1016/j.virol.2015.07.001
PMCID: PMC4619147

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