Article
Adjuvants recognized by toll-like receptors inhibit the induction of polarized type 2 T cell responses by natural attachment (G) protein of respiratory syncytial virus.
Vaccine - 1 Oct 2003
Hancock Gerald E, Heers Kristen M, Pryharski Karin S, Smith Jason D, Tiberio Lorrie
Abstract excerpt
Immunization with native fusion (F) protein from respiratory syncytial virus (RSV) adsorbed to alum adjuvant generates greater than fourfold rises in serum neutralizing antibody titers in approximately 50% of seropositive humans. Using BALB/c mice we demonstrate herein that enhanced neutralization titers and accelerated clearance of virus from the lungs after challenge are possible if the attachment (G)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
