Article
HLA-DP genes polymorphisms associate with hepatitis B surface antigen kinetics and seroclearance during nucleot(s)ide analogue therapy.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2015
Hosaka Tetsuya, Suzuki Fumitaka, Kobayashi Masahiro, Fukushima Taito, Kawamura Yusuke, Sezaki Hitomi, Akuta Norio, Suzuki Yoshiyuki, Saitoh Satoshi, Arase Yasuji, Ikeda Kenji, Kobayashi Mariko, Kumada Hiromitsu
Abstract excerpt
BACKGROUND & AIMS: Genome-wide association studies (GWAS) recently indicated that polymorphisms in the human leucocyte antigen (HLA)-DP genes were associated with risk of persistent hepatitis B virus (HBV) infection and clearance of HBV, but the effect of HLA-DP gene polymorphisms on the effect of antiviral therapy was unknown. We here investigated whether such polymorphisms were associated with decreases in...
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