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Article

HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.

Journal of virology - 1 Nov 2013

Zhang Qi, Yin Jianhua, Zhang Yuwei, Deng Yang, Ji Xiaowei, Du Yan, Pu Rui, Han Yifang, Zhao Jun, Han Xue, Zhang Hongwei, Cao Guangwen

Abstract excerpt

Genetic polymorphisms of HLA-DP have been associated with hepatitis B virus (HBV) persistence. We aimed to determine the effect of HLA-DP polymorphisms on the generation of HBV mutations and their interactions on the outcomes of HBV infection. rs3077, rs3135021, rs9277535, and rs2281388 were genotyped in 1,342 healthy controls, 327 HBV clearance subjects, and 2,736 HBV-positive subjects, including 1,108...

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Share to Carcinoma, Hepatocellular
Share to Hepatitis B, Chronic
Share to Hepatitis B Surface Antigens
Share to Hepatitis B virus
Share to HLA-DP Antigens
Share to Liver Cirrhosis
Share to Liver Neoplasms
Share to Real-Time Polymerase Chain Reaction

Source

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Identifiers

PMID: 24006435
DOI: 10.1128/JVI.02073-13
PMCID: PMC3807892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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