Article
Protective effects of HLA-DPA1/DPB1 variants against Hepatitis B virus infection in an Indonesian population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2016
Wasityastuti Widya, Yano Yoshihiko, Ratnasari Neneng, Triyono Teguh, Triwikatmani Catharina, Indrarti Fahmi, Heriyanto Didik Setyo, Yamani Laura Navika, Liang Yujiao, Utsumi Takako, Hayashi Yoshitake
Abstract excerpt
Human leukocyte antigen (HLA) DPA1/DPB1 variants have been reported to influence Hepatitis B virus (HBV) infection. HLA-DPA1/DPB1 plays a pivotal role in antigen presentation to CD4(+) helper T cells and influences the outcome of HBV infection. To investigate the influence of HLA-DP variants on the outcome of HBV infection in an Indonesian population where it has the third-highest prevalence of HBV infection...
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