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Article

Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population.

Hepatology (Baltimore, Md.) - 1 Feb 2011

Guo Xiuchan, Zhang Yong, Li Ji, Ma Jingchen, Wei Zuli, Tan Wenjie, O'Brien Stephen J

Abstract excerpt

Chronic hepatitis B virus (HBV) infection is a major health issue, especially in Asia. A recent genome-wide association study (GWAS) implicated genetic variants in the human leukocyte antigen (HLA)-DP locus associated with chronic hepatitis B in Japanese and Thai populations. To confirm whether the polymorphisms at the HLA-DP genes are associated with persistent chronic HBV infection in Han Chinese, we conducted...

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Identifiers

PMID: 21274863
DOI: 10.1002/hep.24048
PMCID: PMC3056070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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