Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel variant marking HLA-DP expression levels predicts recovery from hepatitis B virus infection.

Journal of virology - 1 Jun 2012

Thomas Rasmi, Thio Chloe L, Apps Richard, Qi Ying, Gao Xiaojiang, Marti Darlene, Stein Judy L, Soderberg Kelly A, Moody M Anthony, Goedert James J, Kirk Gregory D, Hoots W Keith, Wolinsky Steven, Carrington Mary

Abstract excerpt

Variants near the HLA-DP gene show the strongest genome-wide association with chronic hepatitis B virus (HBV) infection and HBV recovery/persistence in Asians. To test the effect of the HLA-DP region on outcomes to HBV infection, we sequenced the polymorphic HLA-DPB1 and DPA1 coding exons and the corresponding 3' untranslated regions (3'UTRs) in 662 individuals of European-American and African-American ancestry....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Hepatitis B

Share to Hepatitis B virus

Share to HLA-DP alpha-Chains

Share to HLA-DP beta-Chains

Share to Racial Groups

Source

Open in PubMed Open full text

Identifiers

PMID: 22496224
DOI: 10.1128/JVI.00406-12
PMCID: PMC3393572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel variant marking HLA-DP expression levels predicts recovery from hepatitis B virus infection.PMID 22496224Read ↗

Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development.Semantic proximity Read ↗

Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.Semantic proximity Read ↗

Protective effects of HLA-DPA1/DPB1 variants against Hepatitis B virus infection in an Indonesian population.Semantic proximity Read ↗

Variation of HLA-DPB1 Gene in Hepatitis B InfectionSemantic proximity Read ↗

Variation and expression of HLA-DPB1 gene in HBV infection.Semantic proximity Read ↗

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.Semantic proximity Read ↗

A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese.Semantic proximity Read ↗

HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.Semantic proximity Read ↗

Strong influence of human leukocyte antigen (HLA)-DP gene variants on development of persistent chronic hepatitis B virus carriers in the Han Chinese population.Semantic proximity Read ↗

Association of the rs3077 and rs9277535 polymorphisms in HLA-DP with hepatitis B virus infection and spontaneous clearance: a meta-analysis.Semantic proximity Read ↗

New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia.Semantic proximity Read ↗

Genetic variants in human leukocyte antigen/DP-DQ influence both hepatitis B virus clearance and hepatocellular carcinoma development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.