Article
Polymorphisms of HLA-DP are associated with response to peginterferon in Caucasian patients with chronic hepatitis B.
Alimentary pharmacology & therapeutics - 1 Oct 2014
Brouwer W P, Sonneveld M J, Tabak F, Simon K, Cakaloglu Y, Akarca U S, Zeuzem S, Ferenci P, Heathcote J E, de Knegt R J, Boonstra A, Hansen B E, Janssen H L A
Abstract excerpt
BACKGROUND: Polymorphisms of the HLA-DP gene are associated with the natural clearance of the hepatitis B virus in Asian patients. AIM: To investigate the association of HLA-DP polymorphisms with response to peginterferon (PEG-IFN) in Caucasian chronic hepatitis B (CHB) patients. METHODS: We studied 262 Caucasian chronic hepatitis B patients infected with HBV genotype A or D, treated with PEG-IFN for 1 year in...
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