Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development.

doi:10.1038/srep14933

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development.

Scientific reports - 14 Oct 2015

Yu Lei, Cheng Yi-ju, Cheng Ming-liang, Yao Yu-mei, Zhang Quan, Zhao Xue-ke, Liu Hua-juan, Hu Ya-xin, Mu Mao, Wang Bi, Yang Guo-zhen, Zhu Li-li, Zhang Shuai

Abstract excerpt

Hepatitis B virus (HBV) infection is the predominant risk factor for chronic hepatitis B (CHB), liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Recently, genome-wide association studies have identified human leukocyte antigen (HLA)-DP polymorphisms (rs3077 and rs9277535) as a new chronic...

Topics

Carcinoma, Hepatocellular
Causality
China
Comorbidity
Female
Genetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DP Antigens

Hepatitis B

Humans

Liver Neoplasms

Male

Polymorphism, Single Nucleotide

Precancerous Conditions

Prevalence

Risk Assessment

Virus Latency

Source

Open in PubMed Open full text

Identifiers

PMID: 26462556
DOI: 10.1038/srep14933
PMCID: PMC4604517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26462556-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.