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Article

Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development.

Scientific reports - 14 Oct 2015

Yu Lei, Cheng Yi-ju, Cheng Ming-liang, Yao Yu-mei, Zhang Quan, Zhao Xue-ke, Liu Hua-juan, Hu Ya-xin, Mu Mao, Wang Bi, Yang Guo-zhen, Zhu Li-li, Zhang Shuai

Abstract excerpt

Hepatitis B virus (HBV) infection is the predominant risk factor for chronic hepatitis B (CHB), liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Recently, genome-wide association studies have identified human leukocyte antigen (HLA)-DP polymorphisms (rs3077 and rs9277535) as a new chronic HBV infection susceptibility locus. Since then, the relationship between HLA-DP polymorphisms and various outcomes of...

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Share to Carcinoma, Hepatocellular
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Share to Genetic Predisposition to Disease
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Identifiers

PMID: 26462556
DOI: 10.1038/srep14933
PMCID: PMC4604517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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