Article
Genetic convergence in the adaptation of dogs and humans to the high-altitude environment of the tibetan plateau.
Genome biology and evolution - 1 Aug 2014
Wang Guo-Dong, Fan Ruo-Xi, Zhai Weiwei, Liu Fei, Wang Lu, Zhong Li, Wu Hong, Yang He-Chuan, Wu Shi-Fang, Zhu Chun-Ling, Li Yan, Gao Yun, Ge Ri-Li, Wu Chung-I, Zhang Ya-Ping
Abstract excerpt
The high-altitude hypoxic environment represents one of the most extreme challenges for mammals. Previous studies of humans on the Tibetan plateau and in the Andes Mountains have identified statistical signatures of selection in different sets of loci. Here, we first measured the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands. We found that the hemoglobin levels are very similar...
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