Article
Population variation revealed high-altitude adaptation of Tibetan mastiffs.
Molecular biology and evolution - 1 May 2014
Li Yan, Wu Dong-Dong, Boyko Adam R, Wang Guo-Dong, Wu Shi-Fang, Irwin David M, Zhang Ya-Ping
Abstract excerpt
With the assistance of their human companions, dogs have dispersed into new environments during the expansion of human civilization. Tibetan Mastiff (TM), a native of the Tibetan Plateau, was derived from the domesticated Chinese native dog and, like Tibetans, has adapted to the extreme environment of high altitude. Here, we genotyped genome-wide single-nucleotide polymorphisms (SNPs) from 32 TMs and compared...
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