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Article

Shared and unique signals of high-altitude adaptation in geographically distinct Tibetan populations.

PloS one - 1 Jan 2014

Wuren Tana, Simonson Tatum S, Qin Ga, Xing Jinchuan, Huff Chad D, Witherspoon David J, Jorde Lynn B, Ge Ri-Li

Abstract excerpt

Recent studies have used a variety of analytical methods to identify genes targeted by selection in high-altitude populations located throughout the Tibetan Plateau. Despite differences in analytic strategies and sample location, hypoxia-related genes, including EPAS1 and EGLN1, were identified in multiple studies. By applying the same analytic methods to genome-wide SNP information used in our previous study of...

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Topics

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Share to Adaptation, Physiological
Share to Altitude

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Basic Helix-Loop-Helix Transcription Factors

Share to DNA, Mitochondrial

Share to Heme Oxygenase (Decyclizing)

Share to Hypoxia

Share to Hypoxia-Inducible Factor-Proline Dioxygenases

Source

Open in PubMed Open full text

Identifiers

PMID: 24642866
DOI: 10.1371/journal.pone.0088252
PMCID: PMC3958363

Genes

EGLN1
EPAS1
HBB
HBG2
HFE
HMOX2
PKLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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