Association between the common functional FKBP5 variant (rs1360780) and brain structure in a non-clinical population.

doi:10.1016/j.jpsychires.2014.07.009

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Article

Association between the common functional FKBP5 variant (rs1360780) and brain structure in a non-clinical population.

Journal of psychiatric research - 1 Nov 2014

Fujii Takashi, Ota Miho, Hori Hiroaki, Hattori Kotaro, Teraishi Toshiya, Sasayama Daimei, Higuchi Teruhiko, Kunugi Hiroshi

Abstract excerpt

FK506 binding protein 5 (FKBP5) is induced by stress and regulates glucocorticoid receptor sensitivity. The T allele of the single nucleotide polymorphism (SNP) FKBP5 rs1360780 (C/T) is associated with an increased risk of post-traumatic stress disorder (PTSD) and reduced hippocampal volume in traumatized or depressed subjects. To examine whether this SNP affects brain structures that regulate stress response, we...

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Identifiers

PMID: 25088286
DOI: 10.1016/j.jpsychires.2014.07.009

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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