The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals.

doi:10.1038/srep06696

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Article

The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals.

Scientific reports - 21 Oct 2014

Fujii Takashi, Ota Miho, Hori Hiroaki, Hattori Kotaro, Teraishi Toshiya, Matsuo Junko, Kinoshita Yukiko, Ishida Ikki, Nagashima Anna, Kunugi Hiroshi

Abstract excerpt

The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Binding Protein 5 (FKBP5) gene has been reported to be associated with an altered response of the hypothalamic-pituitary-adrenal (HPA) axis and the development of stress-related psychiatric disorders such as posttraumatic stress disorder (PTSD). In the present study, we examined whether this SNP is associated with cognitive function in a...

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PMID: 25331639
DOI: 10.1038/srep06696
PMCID: PMC4204028

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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