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Article

Effect of the -2081G/A polymorphism of the TLR4 gene and its interaction with Helicobacter pylori infection on the risk of gastric cancer in Chinese individuals.

Genetic testing and molecular biomarkers - 1 Sept 2014

Li Ping, He Cai-Yun, Xu Qian, Sun Li-Ping, Ha Min-Wen, Yuan Yuan

Abstract excerpt

AIMS: Toll-like receptor 4 (TLR4) plays an important role in gastric carcinoma. Using a case-control study, we analyzed the genotypic distribution of TLR4 rs10983755 (-2081G/A) and rs11536878 in a Chinese population and investigated the effect of their interactions with Helicobacter pylori infection on susceptibility to gastric cancer (GC) and atrophic gastritis (AG). METHODS: In this study, 409 and 581 cases of...

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Source

Identifiers

PMID: 25084512
DOI: 10.1089/gtmb.2014.0047

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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