Article
Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2015
Tang Fu-Bing, Li Zhe-Xuan, Wang Yu-Mei, Zhang Lian, Ma Jun-Ling, Zhou Tong, Zhang Yang, Gao Juan-Juan, Wu Si, Yang Tian, You Wei-Cheng, Pan Kai-Feng
Abstract excerpt
Genetic polymorphisms of Toll-like receptor (TLR) 1 and 10 may influence Helicobacter pylori (H. pylori) susceptibility. To evaluate associations between TLR1 and 10 polymorphisms, H. pylori infection, and precancerous gastric lesions, a population-based study was conducted in a high-risk Chinese population. Three single-nucleotide polymorphisms, TLR1 rs4833095, TLR10 rs10004195, and TLR10 rs4129009 were...
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