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Article

Genetic variations of TLR5 gene interacted with Helicobacter pylori infection among carcinogenesis of gastric cancer.

Oncotarget - 9 May 2017

Xu Tianwen, Fu Deqiang, Ren Yi, Dai Yijun, Lin Jianguang, Tang Liming, Ji Jian

Abstract excerpt

Gastric cancer (GC) ranks the second prevalent cancer type and the second cancer-related death in China. However, the precise mechanisms of GC development remain poorly understood. Chronic infection with Helicobacter pylori is the strongest identified risk factor for GC. Toll-like receptor (TLR) genes, which play critical roles in Helicobacter pylori induced chronic inflammation, may also be implicated in GC...

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Source

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Identifiers

PMID: 28404962
DOI: 10.18632/oncotarget.16050
PMCID: PMC5458185

Genes

TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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