Genetic variants in the regulation region of TLR4 reduce the gastric cancer susceptibility.

doi:10.1016/j.gene.2020.145181

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Article

Genetic variants in the regulation region of TLR4 reduce the gastric cancer susceptibility.

Gene - 30 Jan 2021

Li Ze, Gao Hui, Liu Yang, Wu Hongjiao, Li Weiyuan, Xing Yunce, Zhang Zhi, Zhang Xuemei

Abstract excerpt

Gastric cancer (GC) is one of the most common cancers diagnosed in China. It has been suggested that the genetic polymorphisms of Toll-like receptors (TLRs) might be in close relation to tumorigenesis and development of gastric cancer. In this study, we performed a case-control study to investigate the genetic polymorphisms of TLR3, 4, 5, 7 with the genetic susceptibility of gastric cancer. TLRs gene...

Topics

Adult
Aged
Aged, 80 and over
Case-Control Studies
China
Female
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Logistic Models
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Odds Ratio

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Stomach Neoplasms

Source

Open in PubMed

Identifiers

PMID: 33007372
DOI: 10.1016/j.gene.2020.145181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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