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Article

Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese.

Helicobacter - 1 Feb 2009

Hishida Asahi, Matsuo Keitaro, Goto Yasuyuki, Mitsuda Yoko, Hiraki Akio, Naito Mariko, Wakai Kenji, Tajima Kazuo, Hamajima Nobuyuki

Abstract excerpt

BACKGROUND: Toll-like receptor 4 (TLR4) Asp299Gly and Thr399Ile polymorphisms were reported to be a risk factor of gastric carcinoma or its precursors in Caucasian and Indian population, but these polymorphisms are absent in Japanese. We investigated the associations of TLR4+3725 G/C polymorphism, another functional polymorphism of TLR4, with risk of gastric cancer and gastric atrophy in Japanese. MATERIALS AND...

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Source

Identifiers

PMID: 19191896
DOI: 10.1111/j.1523-5378.2009.00659.x

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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