Article
Genetic variants of toll-like receptor 2 and 5, helicobacter pylori infection, and risk of gastric cancer and its precursors in a chinese population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2011
Zeng Hong-Mei, Pan Kai-Feng, Zhang Yang, Zhang Lian, Ma Jun-Ling, Zhou Tong, Su Hui-Juan, Li Wen-Qing, Li Ji-You, Gerhard Markus, Classen Meinhard, You Wei-Cheng
Abstract excerpt
BACKGROUND: Genetic polymorphisms of Toll-like receptors (TLR) may influence the outcome of Helicobacter pylori infection and play important roles in gastric carcinogenesis. To screen the genetic variants of TLR2 and TLR5, and evaluate their associations with gastric cancer (GC) and its precursors, a population-based study was conducted in Linqu County, Shandong Province, China. METHODS: Genetic variants were...
Topics
- Case-Control Studies
- China
- Female
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Male
- Middle Aged