Article
TLR4 polymorphisms associated with developing gastric pre-cancer lesions in a Chinese Han population.
Human immunology - 1 Feb 2014
Fan Yao-fu, Wu Yan-min, Liu Hao, Yu Yuan, Jiang Yang-yang, Xue Yu-zheng, Liu Zong-liang, Wei Mu-Xin
Abstract excerpt
Helicobacter pylori infection is a risk factor for gastric cancer. In addition, toll-like receptor 4 (TLR4) plays a fundamental role in pathogen recognition and activation of innate immunity. This study investigated the association of TLR4 polymorphisms with a risk of intestinal metaplasia (IM) and intraepithelial neoplasia (IN) in a Chinese Han population. This study analyzed TLR4 gene polymorphisms in 333...
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