A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.

doi:10.1093/hmg/ddu398

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.

Human molecular genetics - 20 Dec 2014

Julià Antonio, Domènech Eugeni, Chaparro María, García-Sánchez Valle, Gomollón Fernando, Panés Julián, Mañosa Míriam, Barreiro-De Acosta Manuel, Gutiérrez Ana, Garcia-Planella Esther, Aguas Mariam, Muñoz Fernando, Esteve Maria, Mendoza Juan L, Vera Maribel, Márquez Lucía, Tortosa Raül, López-Lasanta María, Alonso Arnald, Gelpí Josep L, García-Montero Andres C, Bertranpetit Jaume, Absher Devin, Myers Richard M, Gisbert Javier P, Marsal Sara

Abstract excerpt

The genetic analysis of ulcerative colitis (UC) has provided new insights into the etiology of this prevalent inflammatory bowel disease. However, most of the heritability of UC (>70%) has still not been characterized. To identify new risk loci for UC we have performed the first genome-wide association study (GWAS) in a Southern European population and undertaken a meta-analysis study combining the newly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

Share to Colitis, Ulcerative

Share to DNA, Intergenic

Share to Genetic Loci

Share to Genome-Wide Association Study

Share to Membrane Glycoproteins

Share to Odds Ratio

Source

Open in PubMed

Identifiers

PMID: 25082827
DOI: 10.1093/hmg/ddu398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.PMID 25082827Read ↗

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.Semantic proximity Read ↗

Genome-wide association identifies multiple ulcerative colitis susceptibility loci.Semantic proximity Read ↗

Common variants at five new loci associated with early-onset inflammatory bowel disease.Semantic proximity Read ↗

Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

The genetics of Crohn's disease and ulcerative colitis--status quo and beyond.Semantic proximity Read ↗

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.Semantic proximity Read ↗

Genetics of ulcerative colitisSemantic proximity Read ↗

The genetic background of inflammatory bowel disease: from correlation to causality.Semantic proximity Read ↗

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).Semantic proximity Read ↗

Case-case genome-wide association analysis identifying genetic loci with divergent effects on Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.Semantic proximity Read ↗

Rare and common variant discovery in complex disease: the IBD case studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.