Article
The genetic background of inflammatory bowel disease: from correlation to causality.
The Journal of pathology - 1 Jan 2017
Uniken Venema Werna Tc, Voskuil Michiel D, Dijkstra Gerard, Weersma Rinse K, Festen Eleonora Am
Abstract excerpt
Recent studies have greatly improved our insight into the genetic background of inflammatory bowel disease (IBD). New high-throughput technologies and large-scale international collaborations have contributed to the identification of 200 independent genetic risk loci for IBD. However, in most of these loci, it is unclear which gene conveys the risk for IBD. More importantly, it is unclear which variant within or...
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