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Article

The balance of cell surface and soluble type III TGF-β receptor regulates BMP signaling in normal and cancerous mammary epithelial cells.

Neoplasia (New York, N.Y.) - 1 Jun 2014

Gatza Catherine E, Elderbroom Jennifer L, Oh Sun Young, Starr Mark D, Nixon Andrew B, Blobe Gerard C

Abstract excerpt

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily that are over-expressed in breast cancer, with context dependent effects on breast cancer pathogenesis. The type III TGF-β receptor (TβRIII) mediates BMP signaling. While TβRIII expression is lost during breast cancer progression, the role of TβRIII in regulating BMP signaling in normal mammary epithelium and breast cancer cells has not been...

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Identifiers

PMID: 25077702
DOI: 10.1016/j.neo.2014.05.008
PMCID: PMC4198744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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