Article
CHI3L1 polymorphisms associate with asthma in a Taiwanese population.
BMC medical genetics - 23 Jul 2014
Tsai Yishan, Ko Yingchin, Huang Mingshyan, Lin Mengchih, Wu Chaochien, Wang Chinchou, Chen Yunxuan, Li Jianing, Tseng Yuting, Wang Tsunai
Abstract excerpt
BACKGROUND: A genome-wide association study uncovered Chitinase 3 like 1 (CHI3L1) as a candidate gene for asthma susceptibility. CHI3L1, which encodes the YKL-40 protein, is associated with asthma in Western European and American populations and with atopy in a Korean population. However, asthma-associated polymorphisms remain unknown for a Taiwanese population. METHODS: We enrolled 628 adult asthmatic patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.