Article
Chitinase 3-like 1 polymorphisms and risk of chronic obstructive pulmonary disease and asthma in a Chinese population.
The journal of gene medicine - 1 Sept 2020
Yu Tao, Niu Wenquan, Niu Hongtao, Duan Ruirui, Dong Fen, Yang Ting
Abstract excerpt
BACKGROUND: Chitinase 3-like 1 (CHI3L1) plays an important role in airway inflammation and tissue remodeling; however, its pathogenic role in lung diseases remains unclear. In the present study, we investigated whether CHI3L1 polymorphisms are associated with the risk of chronic obstructive pulmonary disease (COPD) and asthma in a Chinese population. METHODS: We detected seven single nucleotide polymorphisms in...
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