Article
CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development.
BMC pulmonary medicine - 18 May 2016
Usemann Jakob, Frey Urs, Mack Ines, Schmidt Anne, Gorlanova Olga, Röösli Martin, Hartl Dominik, Latzin Philipp
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never been addressed whether SNPs in CHI3L1 and cord blood YKL-40 levels could already serve as potential biomarkers for milder forms of asthma. We assessed in an unselected population whether SNPs in CHI3L1 and cord blood...
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