Article
The CHI3L1 rs4950928 polymorphism is associated with asthma-related hospital admissions in children and young adults.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 May 2011
Cunningham Jason, Basu Kaninika, Tavendale Roger, Palmer Colin N A, Smith Helen, Mukhopadhyay Somnath
Abstract excerpt
BACKGROUND: Asthma exacerbations are the commonest cause of medical admissions in childhood. These have a significant effect on quality of life and are a major financial burden on worldwide healthcare services. A range of gene-environment interactions may influence the course and severity of asthma in children and their response to medication. The Chitinase 3-like 1 (CHI3L1)-131C>G genotype (rs4950928) is...
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