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Article

Significant Association of Chitinase 3-like 1 Genotypes to Asthma Risk in Taiwan.

In vivo (Athens, Greece) - 1 Jan 2000

Chen Guan-Liang, Wang Shou-Cheng, Shen Te-Chun, Chang Wen-Shin, Lin Chingju, Hsia Te-Chun, Bau DA-Tian, Tsai Chia-Wen

Abstract excerpt

BACKGROUND/AIM: Chitinase 3-like 1 (CHI3L1) is overexpressed in asthma, and negatively associated with forced expiratory volume in the first second. This study aimed at evaluating whether CHI3L1 genotypes affect asthma risk. MATERIALS AND METHODS: The blood samples of 198 asthma patients and 453 control subjects were collected, and the genotypic patterns of CHI3L1 -131C/G (rs4950928) and -247G/A (rs1262491437)...

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Identifiers

PMID: 33622872
DOI: 10.21873/invivo.12320
PMCID: PMC8045126

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