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Article

Structure-function analysis of Drosophila Notch using genomic rescue transgenes.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Leonardi Jessica, Jafar-Nejad Hamed

Abstract excerpt

One of the evolutionarily conserved posttranslational modifications of the Notch receptors is the addition of an O-linked glucose to epidermal growth factor-like (EGF) repeats with a specific consensus sequence by the protein O-glucosyltransferase Rumi (POGLUT1 in human). Loss of rumi in flies results in a temperature-sensitive loss of Notch signaling. To demonstrate that the Notch receptor itself is the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25053479
DOI: 10.1007/978-1-4939-1139-4_3

Genes

EGF
POGLUT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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