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Article

Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase.

Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2011

Takeuchi Hideyuki, Fernández-Valdivia Rodrigo C, Caswell Devin S, Nita-Lazar Aleksandra, Rana Nadia A, Garner Thomas P, Weldeghiorghis Thomas K, Macnaughtan Megan A, Jafar-Nejad Hamed, Haltiwanger Robert S

Abstract excerpt

Mutations in rumi result in a temperature-sensitive loss of Notch signaling in Drosophila. Drosophila Rumi is a soluble, endoplasmic reticulum-retained protein with a CAP10 domain that functions as a protein O-glucosyltransferase. In human and mouse genomes, three potential Rumi homologues exist: one with a high degree of identity to Drosophila Rumi (52%), and two others with lower degrees of identity but...

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Identifiers

PMID: 21949356
DOI: 10.1073/pnas.1109696108
PMCID: PMC3189016

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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